Benzyl Chloride → 3-Benzyl-5-methyl-1,3,5-oxadiazinane-2,4,6-trione

HRID 463809Notes

Reaction equation

HRID 463809 reaction equation
[CH2:1](Cl)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:9][N:10]1[C:15](=[O:16])[NH:14][C:13](=[O:17])[O:12][C:11]1=[O:18]>>[CH3:9][N:10]1[C:15](=[O:16])[N:14]([CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[C:13](=[O:17])[O:12][C:11]1=[O:18]

Participants

3

Reactant 2

HCID 7503Benzyl ChlorideHCID 202653353-Methyl-1,3,5-oxadiazinane-2,4,6-trione

Product 1

HCID 202653363-Benzyl-5-methyl-1,3,5-oxadiazinane-2,4,6-trioneYield 83%

Procedure

The process described in example 1 is carried out. 15.2 g of benzyl chloride (0.12 mole) are added to the obtained solution of the salt of 3-methyl-1,3,5-oxadiazine-2,4,6-trione. After 3 hours of reaction at a temperature of 60° C., one obtains 19.4 g of 3-methyl-5-benzyl-1,3,5oxadiazine-2,4,6-trione (yield: 83%) which is an asymmetrical disubstituted 1,3,5-oxadiazine trione of the formula (III).

Workup

  1. customAfter 3 hours of reaction at a temperature of 60° C., one

Sources & evidence

ORD record
ord-415fca06f98942c99977c240ccdfba28
Source dataset
uspto-grants-1985_10
Patent number
US04544743

Reaction notes

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