反应详情

2,5-Di(acetoxymethyl)pyridine (0.05 mole) is reduced with lithium aluminum hydride (0.025 mole) in tetrahydrofuran (50 ml.) at 0° C. with stirring. After one hour, water is added to decompose excess hydride, and the mixture is concentrated to dryness. The residue is extracted with hot isopropanol (2×60 ml.) and the extract is concentrated to dryness to give 2,5-di(hydroxymethyl) pyridine.

1. concentrationthe mixture is concentrated to dryness
2. extractionThe residue is extracted with hot isopropanol (2×60 ml.)
3. concentrationthe extract is concentrated to dryness