Triethyl orthoacetate → HCID 20264252, compound

HRID 464118Notes

Reaction equation

HRID 464118 reaction equation
[NH2:1][N:2]1[C:7](=[O:8])[CH:6]=[C:5]([CH3:9])[N:4]=[C:3]1[NH:10][NH2:11].[C:12](OCC)(OCC)(OCC)[CH3:13]>C(O)CCC>[NH2:11][N:10]1[C:3]2=[N:4][C:5]([CH3:9])=[CH:6][C:7](=[O:8])[N:2]2[N:1]=[C:12]1[CH3:13]

Participants

4

Reactant 2

HCID 66221Triethyl orthoacetateHCID 1492084HCID 1492084, compound

Product 1

HCID 20264252HCID 20264252, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

A 3.0 g portion of 3-amino-2-hydrazino-6-methyl-4(3H)-pyrimidinone, 20 ml of triethyl orthoacetate and 100 ml of n-butanol was reacted as described in Example 1, giving 2.36 g of the desired intermediate, mp 287°-289° C.

Sources & evidence

ORD record
ord-9a6c81b042c34e96afb10916fe5a20f7
Source dataset
uspto-grants-1985_10
Patent number
US04546181

Reaction notes

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