反应详情

A five-liter, three-necked flask equipped with a mechanical stirrer, reflux condenser, and thermometer was charged with toluene (3.3 liters), triphenylphosphine (686 g, 2.62 mole), and pentafluorobenzyl bromide (343 g, 1.31 mole). The contents were stirred and heated slowly to reflux. A white precipitate formed as the reaction progressed. At the completion of the reaction the flask was cooled to ambient temperature and the solid product was filtered and washed with hot toluene (2.6 liters). These solids were dried in a vacuum desiccator to give a 90% yield of pentafluorobenzyltriphenylphosphonium bromide.

1. customA five-liter, three-necked flask equipped with a mechanical stirrer
2. temperaturereflux condenser
3. temperatureheated slowly
4. temperatureto reflux
5. customA white precipitate formed as the reaction
6. customAt the completion of the reaction the flask
7. filtrationthe solid product was filtered
8. washwashed with hot toluene (2.6 liters)
9. customThese solids were dried in a vacuum desiccator