反应详情

[B] 4 g of 2,3-dichloro-5-trifluoromethylpyridine was added to an aqueous solution of 2.4 g of sodium hydroxide dissolved in 12.5 ml of water, and 12.5 ml of dimethyl sulfoxide was further added thereto. The solution was reacted at 110° C. for 1 hour while stirring. After completion of the reaction, the reaction product was allowed to cool and made acidic with concentrated hydrochloric acid to obtain a precipitate. The thus obtained precipitate was collected by filtration to obtain 2.5 g of the titled compound.

1. customThe solution was reacted at 110° C. for 1 hour
2. customAfter completion of the reaction
3. temperatureto cool
4. customto obtain a precipitate
5. filtrationThe thus obtained precipitate was collected by filtration