HuagongsheHuagongshe Chemistry Print Report · For research reference only
Vanillin → E-8-(4-Acetoxy-3-methoxybenzylidene)-5,6,7,8-tetrahydro-4-methylquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Vanillin | HCID 1183 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 5,6,7,8-Tetrahydro-4-methylquinoline | HCID 185667 | — |
| Catalyst | Zincchloride | HCID 3007855 | — |
| Product | E-8-(4-Acetoxy-3-methoxybenzylidene)-5,6,7,8-tetrahydro-4-methylquinoline | HCID 10245630 | — |
Reaction Steps
A mixture of 5,6,7,8-tetrahydro-4-methylquinoline (5.2 g), vanillin (5.37 g), zinc chloride (0.3 g) and acetic anhydride (50 ml) were refluxed under nitrogen for 16 hours. The solvent was removed by evaporation and the resulting residue was neutralised (Na2CO3) in the presence of ethyl acetate and was then extracted with ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04547510 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-4f49006b3a8c48e883695fcfd9e08f68 |
| Source note | uspto-grants-1985_10 |