HCID 70492344, compound → HCID 135453936, compound

HRID 464328Notes

Reaction equation

HRID 464328 reaction equation
Cl.C([O:5][C:6]1[CH:23]=[CH:22][C:9](/[CH:10]=[C:11]2\[CH2:12][CH2:13][CH2:14][C:15]3[CH:16]=[C:17]([CH3:21])[CH:18]=[N:19][C:20]\2=3)=[CH:8][C:7]=1[O:24][CH3:25])(=O)C>Cl>[OH:5][C:6]1[CH:23]=[CH:22][C:9](/[CH:10]=[C:11]2\[CH2:12][CH2:13][CH2:14][C:15]3[CH:16]=[C:17]([CH3:21])[CH:18]=[N:19][C:20]\2=3)=[CH:8][C:7]=1[O:24][CH3:25]

Participants

3

Reactant 1

HCID 70492344HCID 70492344, compound

Product 1

HCID 135453936HCID 135453936, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A mixture of E-5,6,7,8-tetrahydro-8-(4-acetoxy-3-methoxybenzylidene)-3-methylquinoline HCl (prepared according to Example 8) (3.0 g) and 2N HCl (50 ml) were heated for 1 hour on a steam bath. After cooling the yellow crystals were removed by filtration, washed with diethyl ether and then dried to give the title compound as the hydrochloride salt (2.5 g). m.p. 257°-60° C.

Workup

  1. temperaturewere heated for 1 hour on a steam bath
  2. temperatureAfter cooling the yellow crystals
  3. customwere removed by filtration
  4. washwashed with diethyl ether
  5. customdried

Sources & evidence

ORD record
ord-8d5c217f537a40958940fc4ae6b2f2bd
Source dataset
uspto-grants-1985_10
Patent number
US04547510

Reaction notes

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