HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(4-Chlorobenzyl)-2-methylthiopyrimid-4-one → HCID 54538157, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(4-Chlorobenzyl)-2-methylthiopyrimid-4-one | HCID 12945980 | — |
| Reactant | N~1~-Methyl-N~1~-(pyridin-2-yl)propane-1,3-diamine | HCID 20262876 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 54538157 | HCID 54538157 | — |
Reaction Steps
2-[N-(3-aminopropyl)-N-methylamino]pyridine (1.0 g) and 2-methylthio-5-(4-chlorobenzyl)pyrimid-4-one (1.33 g) were heated together under reflux in pyridine (3 ml) for 20 hr. The mixture was stripped and the residue recrystallised twice from ethanol to give 2-[3-(N-methyl-N-pyrid-2-ylamino) propylamino]-5-(4-chlorobenzyl)pyrimid-4-one 0.5H2O. 1.16 g (59%) mp ca. 65° C. (softens).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04547506 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-8606a3887d7548c29ad5e868f49bfa4a |
| Source note | uspto-grants-1985_10 |