HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylthio-5-(3,4-methylenedioxybenzyl)pyrimid-4-one → 2-[3-(N-propyl-N-pyrid-2-ylamino)propylamino]-5-(3,4-methylenedioxybenzyl) pyrimid-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylthio-5-(3,4-methylenedioxybenzyl)pyrimid-4-one | HCID 12945157 | — |
| Reactant | 2-[N-(3-aminopropyl)-N-propylamino]pyridine | HCID 20186605 | — |
| Product | 2-[3-(N-propyl-N-pyrid-2-ylamino)propylamino]-5-(3,4-methylenedioxybenzyl) pyrimid-4-one | HCID 54430574 | — |
Reaction Steps
2-[N-(3-aminopropyl)-N-propylamino]pyridine (1.0 g) and 2-methylthio-5-(3,4-methylenedioxybenzyl)pyrimid-4-one (1.14 g) were heated together under reflux for 16 hr. After stripping, the residue was crystallised from ethanol/water to give 2-[3-(N-propyl-N-pyrid-2-ylamino)propylamino]-5-(3,4-methylenedioxybenzyl) pyrimid-4-one 1H2O, 1.47 g (81%) mp 86°-92° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04547506 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-1286dcadaada4f1a9672a358d3c9878f |
| Source note | uspto-grants-1985_10 |