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HCID 12783831、化合物 → 2-[3-(N-benzyl-N-pyrid-2-ylamino)propylamino]-5-(5,6-dimethylpyrid-3-ylmethyl)pyrimid-4-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | HCID 12783831 | HCID 12783831 | — |
| 反応物 | 2-[N-(3-aminopropyl)-N-benzylamino)pyridine | HCID 20150364 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 2-[3-(N-benzyl-N-pyrid-2-ylamino)propylamino]-5-(5,6-dimethylpyrid-3-ylmethyl)pyrimid-4-one | HCID 20262889 | — |
反応手順
2-[N-(3-aminopropyl)-N-benzylamino]pyridine (1 g) and 2-nitroamino-5-(5,6-dimethylpyrid-3-ylmethyl)pyrimid-4-one (0.94 g) were heated together under reflux in pyridine (5 ml) for 20 hrs. After stripping the resulting solid was recrystallized from ethanol/water to give 2-[3-(N-benzyl-N-pyrid-2-ylamino)propylamino]-5-(5,6-dimethylpyrid-3-ylmethyl)pyrimid-4-one 0.75 H2O, 0.61 g (38%) m.p. 95°-99° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04547506 |
| 出典データセット | uspto-grants-1985_10 |
| ORD ID | ord-4974f2a97c3d4c14a9d1f882eb801b2b |
| 出典メモ | uspto-grants-1985_10 |