Hydrochloric Acid → Maltol
Reaction equation
[OH:1][CH:2]([C:4]1[O:5][CH:6]=[CH:7][C:8]=1Br)[CH3:3].BrBr.Cl.[OH2:13]>CO>[CH3:8][C:4]1[O:5][CH:6]=[CH:7][C:3](=[O:13])[C:2]=1[OH:1]Participants
6
Reactant 4
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 96 °C
Procedure
To a sample of 2-(1-hydroxyethyl)-3-bromo-furan (0.54 g, 2.8 mmoles) in 15 ml water and 15 ml methanol at 0° C. was added 0.24 g (3.0 mmoles) of bromine. After allowing the reaction to come to room temperature, the reaction was treated with 3 ml of conc. HCl and heated to 96° C. for 2 hours, removing much of the methanol. After cooling, maltol was isolated by the method of Example 1.
Workup
- customthe reaction
- customto come to room temperature
- customremoving much of the methanol
- temperatureAfter cooling
Sources & evidence
- ORD record
- ord-7a3e6bbf569b48bf8548f48c1862d18a
- Source dataset
- uspto-grants-1979_11
- Patent number
- US04173572
Reaction notes
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