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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 4645Generated: October 28, 2026

Phosphorus oxychloride → 2-Amino-5-[3-[3-(piperidinomethyl)phenoxy]propylamino]-1,3,4-oxadiazole

https://huagongshe.com/reaction/4645

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantN-[3-[3-(1-piperidinylmethyl) phenoxy]propyl]-1,2-hydrazine dicarboxamideHCID 54294913—
Product2-Amino-5-[3-[3-(piperidinomethyl)phenoxy]propylamino]-1,3,4-oxadiazoleHCID 558675—

Reaction Steps

The compound is prepared by a method analogous to that of Example 40 from N-[3-[3-(1-piperidinylmethyl) phenoxy]propyl]-1,2-hydrazine dicarboxamide and phosphorus oxychloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04727081
Source datasetuspto-grants-1988_02
ORD IDord-ab50ca1c8ca943ada3827a0b5fa3b8c3
Source noteuspto-grants-1988_02