HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 3,7-dihydro-3-butyl-8-methyl-1H-purine-2,6-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | 5,6-Diamino-1-butylpyrimidine-2,4(1H,3H)-dione | HCID 10584108 | — |
| Product | 3,7-dihydro-3-butyl-8-methyl-1H-purine-2,6-dione | HCID 20217043 | — |
Reaction Steps
A solution of 7.6 g of 1-butyl-5,6-diamino-2,4-(1H,3H)-pyrimidinedione in 20 ml of acetic acid was refluxed for 2 hours. The solution was evaporated. The residue was refluxed in 40 ml of 2N NaOH for 2 hours and then neutralized with 5N HCl. The crystals were filtered off and recrystallized from 350 ml ethanol. Yield 1.8 g (21%) (XXXXVII) NMR (see Table I).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04548818 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-633d4357fff84334b4e6d78695f1470d |
| Source note | uspto-grants-1985_10 |