1-(4-(3-Aminophenyl)thiazol-2-yl)guanidine → HCID 178512249, compound

Participants

Reaction Steps

A solution of 9.33 gm of 2-guanidino-4-(3-amino-phenyl)-thiazole and 3.93 gm of ethyl N-cyano-formamidate in 65 ml of ethanol was stirred at room temperature overnight. The crystalline product which separated out was collected by filtration, washed with cold ethanol and dried, yielding 9.2 gm of the title compound, mp. 215° C. (dec.)

Provenance & Evidence