反应详情

温度

120 °C

A mixture of 23.3 gm of 2-guanidino-4-(3-amino-phenyl)-thiazole, 18.5 gm of ethyl ortoformate and 4.2 gm of cyanamide was heated at 120° C. for 15 minutes, cooled to room temperature, treated with ethanol and filtered, yielding 23 gm of the title compound, m.p. 214°-216° C. (dec.).

1. temperaturecooled to room temperature
2. filtrationfiltered