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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 464698Generated: October 29, 2026

Ethanol → HCID 178512249, compound

https://huagongshe.com/reaction/464698

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantCyanamideHCID 9864—
Reactant1-(4-(3-Aminophenyl)thiazol-2-yl)guanidineHCID 178512611—
ProductHCID 178512249HCID 178512249—

Reaction Conditions

Temperature120 °C

Reaction Steps

A mixture of 23.3 gm of 2-guanidino-4-(3-amino-phenyl)-thiazole, 18.5 gm of ethyl ortoformate and 4.2 gm of cyanamide was heated at 120° C. for 15 minutes, cooled to room temperature, treated with ethanol and filtered, yielding 23 gm of the title compound, m.p. 214°-216° C. (dec.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04548944
Source datasetuspto-grants-1985_10
ORD IDord-cbdacad7dd35416c9c1077f44db5c7c7
Source noteuspto-grants-1985_10