HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(2,2,2-Trifluoroethoxy)pyridin-3-amine → 1-(2,6-Dichlorobenzoyl)-3-(6-(2,2,2-Trifluoroethoxy)-3-Pyridinyl)Urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine | HCID 543156 | — |
| Reactant | 2,6-Dichlorobenzoyl isocyanate | HCID 12912739 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 1-(2,6-Dichlorobenzoyl)-3-(6-(2,2,2-Trifluoroethoxy)-3-Pyridinyl)Urea | HCID 20387352 | — |
Reaction Steps
2-(2,2,2-Trifluoroethoxy)-5-aminopyridine (0.5 gram) and 2,6-dichlorobenzoyl isocyanate (0.5 gram) were mixed in ethyl acetate, and the reaction mixture stirred overnight (about 18 hours) at room temperature. Solvent was removed by evaporation and the product residue crystallized from ethyl acetate-hexanes, yield 0.6 gram, m.p., 146°-148° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04173639 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-1252bba9ac114dde8026f99d6dbedbee |
| Source note | uspto-grants-1979_11 |