反应详情

2-(2,2,2-Trifluoroethoxy)-5-aminopyridine (0.5 gram) and 2,6-dichlorobenzoyl isocyanate (0.5 gram) were mixed in ethyl acetate, and the reaction mixture stirred overnight (about 18 hours) at room temperature. Solvent was removed by evaporation and the product residue crystallized from ethyl acetate-hexanes, yield 0.6 gram, m.p., 146°-148° C.

1. customSolvent was removed by evaporation
2. customthe product residue crystallized from ethyl acetate-hexanes, yield 0.6 gram, m.p., 146°-148° C.