Hydrogen Peroxide → HCID 131711651, compound

HRID 46473Notes

Reaction equation

HRID 46473 reaction equation
[CH:1](=[C:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]1=[O:17])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH:18]O.[OH-].[Na+]>CO>[CH:1](=[C:8]1[CH2:16][C:15]23[O:18][CH:14]2[CH:13]=[CH:12][CH:11]=[C:10]3[C:9]1=[O:17])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 2888762-Benzylidene-1-indanone

Product 1

HCID 131711651HCID 131711651, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2-Benzylidene-1-indanone [3.3 g (0.015 mole), prepared as described in U.S. Pat. No. 3,926,988] is dissolved in 160 ml of MeOH and converted to the epoxide using 3.5 g (0.031 mole) of 30% H2O2 and 3.5 ml (0.014 mole) of 16% NaOH as described in Example 1 to give 3.2 g (90%) of colorless solid; m.p. 115°-117°. A sample crystallized from i-PrOH melts at 118°-120°. Lit m.p. 121°-122° [JACS, 80, 900 (1958)].

Sources & evidence

ORD record
ord-4a80704d065d472ba79b4a05d0d93772
Source dataset
uspto-grants-1979_11
Patent number
US04173634

Reaction notes

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