HCID 20262662, compound → HCID 20262669, compound

HRID 464802Notes

Reaction equation

HRID 464802 reaction equation
C1(C2(C)COC(C)(C)C2)C=CC=CC=1.[CH3:15][C:16]([C:23]1[CH:28]=[CH:27][C:26]([CH3:29])=[CH:25][CH:24]=1)([CH2:19][C:20]([CH3:22])=[CH2:21])[CH:17]=[O:18].[H-].[Al+3].[Li+].[H-].[H-].[H-]>CCOCC>[CH3:15][C:16]([C:23]1[CH:28]=[CH:27][C:26]([CH3:29])=[CH:25][CH:24]=1)([CH2:19][C:20]([CH3:22])=[CH2:21])[CH2:17][OH:18]

Participants

5

Reactant 3

HCID 20262662HCID 20262662, compoundHCID 20262665HCID 20262665, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 20262669HCID 20262669, compoundYield 94%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Following the procedure of part (a) of Example I a 353.5 g sample of 2,4-dimethyl-2-(4-methylphenyl)-4-pentenal was reduced with 30 g of lithium aluminum hydride in 1100 ml of anhydrous ether. Usual workup and distillation afforded 335 g (94% yield) of the desired 2,4-dimethyl-2-(4-methylphenyl)-4-penten-1-ol (bp 136°-138° C./0.7 mm Hg) with a purity of 95%.

Workup

  1. distillationUsual workup and distillation

Sources & evidence

ORD record
ord-3783fcfd63244ccdb9f27a4d0a36a391
Source dataset
uspto-grants-1985_10
Patent number
US04549029

Reaction notes

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