HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 5-[[2-[[(Cyclohexyl)(methyl)amino]methyl]-1-piperidinyl]-acetyl]-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 5-(chloroacetyl)-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one | HCID 10085419 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 5-[[2-[[(Cyclohexyl)(methyl)amino]methyl]-1-piperidinyl]-acetyl]-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one | HCID 13578562 | — |
Reaction Steps
The title compound is prepared analogously to Example 2 from 5-(chloroacetyl)-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one and 2-[[cyclohexyl)(methyl)amino]methyl]piperidine to give colorless crystals, mp. 146°-148° C. (acetonitrile activated charcoal).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04550107 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-e386a395c5c44078a017f1f5bbe3fa3c |
| Source note | uspto-grants-1985_10 |