Hydrazine hydrate (1:1) → HCID 23471413, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 30.2 g of α-methyl-2-(methylthio)-2-imidazoline-1-ethanol, hydroiodide, 5.2 ml of hydrazine hydrate and 200 ml of 2-propanol was refluxed for 4 hours, clarified and cooled at -10° C. The solid was collected, washed with 100 ml of cold 2-propanol, then 200 ml of ether and dried at 60° C. in vacuo, giving 26.0 g of the desired intermediate, mp 140°-142° C.

Provenance & Evidence