Hydrazine hydrate (1:1) → HCID 131714396, compound

HRID 465101Notes

Reaction equation

HRID 465101 reaction equation
[IH:1].CS[C:4]1[CH2:9][CH2:8][CH2:7][CH2:6][N:5]=1.O.[NH2:11][NH2:12]>C(O)C>[IH:1].[NH:11]([C:4]1[CH2:9][CH2:8][CH2:7][CH2:6][N:5]=1)[NH2:12]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 202619156-(Methylsulfanyl)-2,3,4,5-tetrahydropyridine--hydrogen iodide (1/1)

Product 1

HCID 131714396HCID 131714396, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A 6.43 g portion of 3,4,5,6-tetrahydro-2-(methylthio)-pyridine, hydroiodide was added to an ice-cold solution of 1.25 ml of hydrazine hydrate in 35 ml of ethanol. The suspension was stirred at ice bath temperature for 30 minutes, then the solid was collected, washed with ethanol and ether and dried, giving 3.5 g of 2-hydrazino-3,4,5,6-tetrahydropyridine, hydroiodide, which was converted to the monohydronitrate by treatment with silver nitrate in water.

Workup

  1. customthe solid was collected
  2. washwashed with ethanol and ether
  3. customdried

Sources & evidence

ORD record
ord-d5cc8cc06d494f8b8403c10830930c42
Source dataset
uspto-grants-1985_10
Patent number
US04550169

Reaction notes

Loading…