反应详情

温度

130 °C

A 1.0 g portion of 2-hydrazino-3,3'-bipyridine was dissolved in 5 ml of triethyl orthoacetate and heated at 130° C. for 1.5 hours. The volatiles were removed at reduced pressure and the residue purified by chromatography on silica gel, eluting with ethyl acetate:methanol (9:2). The resulting solid was recrystallized from methylene chloride-hexane, giving the desired product as a tan powder, mp 112.5°-115° C.

1. customThe volatiles were removed at reduced pressure
2. customthe residue purified by chromatography on silica gel
3. washeluting with ethyl acetate:methanol (9:2)
4. customThe resulting solid was recrystallized from methylene chloride-hexane