反应详情

温度

100 °C

A 4.15 g portion of 2-hydrazino-3,3'-bipyridine was dissolved in 30 ml of triethyl orthoformate and heated at 100° C. for 2 hours. The volatiles were removed at reduced pressure and the residue purified by chromatography on hydrous magnesium silicate, eluting with ethyl acetate. The solid was recrystallized from methylene chloride-hexane, giving 2.67 g of the desired product, mp 186°-189° C.

1. customThe volatiles were removed at reduced pressure
2. customthe residue purified by chromatography on hydrous magnesium silicate
3. washeluting with ethyl acetate
4. customThe solid was recrystallized from methylene chloride-hexane