反应详情

106.1 g (1.0 mol) of sodium acetylcyanamide and 151.9 g (1.0 mol+20% excess) of benzyl chloride are reacted in 500 ml of dimethylformamide at 100°-112° C. for 4 hours and 20 minutes and the mixture is then filtered. The filtrate is evaporated completly in vacuo on a rotary evaporator at 60° C. to give 146.7 g (88.7% of theory) of a brown viscous residue, which is recrystallised from 290 ml of diisopropyl ether. The yield of pure product of melting point 42° C. is 111.0 g (63.7% of theory).

1. filtrationthe mixture is then filtered
2. customThe filtrate is evaporated completly in vacuo on a rotary evaporator at 60° C.
3. customto give 146.7 g (88.7% of theory) of a brown viscous residue, which
4. customis recrystallised from 290 ml of diisopropyl ether