Ammonia → HCID 20261960, compound

HRID 465163Notes

Reaction equation

HRID 465163 reaction equation
[NH3:1].[N+:2]([C:5]1[CH:10]=[CH:9][C:8]([O:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][C:13]=2[Cl:22])=[CH:7][C:6]=1[NH:23][CH:24]([CH3:29])[C:25](OC)=[O:26])([O-:4])=[O:3]>CO>[N+:2]([C:5]1[CH:10]=[CH:9][C:8]([O:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:20])([F:19])[F:21])=[CH:14][C:13]=2[Cl:22])=[CH:7][C:6]=1[NH:23][CH:24]([CH3:29])[C:25]([NH2:1])=[O:26])([O-:4])=[O:3]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 13195614HCID 13195614, compound

Product 1

HCID 20261960HCID 20261960, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Ammonia was led at room temperature for 28 hours into a solution of 11.7 g of the methyl 2-[N-{2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenyl}amino]propionate, obtained according to Example I, in 100 ml of methanol. After evaporating to dryness under reduced pressure and recrystallizing from acetonitrile, an orange crystalline substance was obtained having a melting-point of 187° C. Elementary analysis: 47.67% C (calculated 47.60), 3.24% H (calculated 3.25) and 10.24% N (calculated 10.41).

Workup

  1. customobtained
  2. customAfter evaporating to dryness under reduced pressure
  3. customrecrystallizing from acetonitrile
  4. customan orange crystalline substance was obtained
  5. customa melting-point of 187° C

Sources & evidence

ORD record
ord-08509c66bbb548b08bbdf532a0abb4e1
Source dataset
uspto-grants-1985_10
Patent number
US04550205

Reaction notes

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