Methyltrimethoxysilane → Octadecylamine

HRID 465297Notes

Reaction equation

C[Si](OC)(OC)OC.[C:9]1([CH3:15])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[N:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH2:21]([NH2:16])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:13][CH2:14][CH2:9][CH2:10][CH2:11][CH2:12][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:9][CH3:15]

Participants

Reactant 2

HCID 14456Methyltrimethoxysilane

HCID 22007288Pyridine toluene

Product 1

HCID 15793Octadecylamine

Procedure

Fractogel phosphate (1; 5 g) containing a trace amount of pyridine was slurried with octadecylamine (6 g) and left at 60° C. for 2 days. Toluene (100 ml) was added to the flask and the mixture refluxed for 24 hours. The mixture was then filtered and the gel washed with methanol to yield Fractogel C-18 (4). The resin was capped with methyltrimethoxy silane in toluene-pyridine at 60° C. for 24 hours. Analysis showed; C, 48.82; H, 6.26; N, 5 1.34%.

Sources & evidence

ORD record: ord-11db8ccf89ef4a3ab2606aaebba153a3
Source dataset: uspto-grants-1992_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05153166

Reaction notes

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