HCID 67833605, compound → HCID 19027066, compound

HRID 465318Notes

Reaction equation

HRID 465318 reaction equation
C([NH:8][S:9]([C:12]1[C:13]2[CH2:28][CH2:27][CH2:26][CH2:25][C:14]=2[C:15]2[NH:16][C:17](=[O:24])[C:18](=[O:23])[N:19]([OH:22])[C:20]=2[CH:21]=1)(=[O:11])=[O:10])(C(OCC)=O)=O>Cl>[OH:22][N:19]1[C:20]2[CH:21]=[C:12]([S:9](=[O:10])(=[O:11])[NH2:8])[C:13]3[CH2:28][CH2:27][CH2:26][CH2:25][C:14]=3[C:15]=2[NH:16][C:17](=[O:24])[C:18]1=[O:23]

Participants

3

Reactant 1

HCID 67833605HCID 67833605, compound

Product 1

HCID 19027066HCID 19027066, compoundYield 89.9%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Conditions

Temperature
0 °C

Procedure

A suspension of 6-ethoxalylaminosulfonyl-7,8,9,10-tetrahydro-4-hydroxybenzo[f]quinoxaline-2,3(1H,4H)-dione (0.20 g, 0.5 mmol) in 7 ml of conc. hydrochloric acid was heated to reflux with stirring for 1.5 h. The mixture was cooled to 0° C. and filtered. The isolated product was washed with water and dried to give 0.14 g (66%) of the title compound.

Workup

  1. temperaturewas heated
  2. temperatureto reflux
  3. filtrationfiltered
  4. washThe isolated product was washed with water
  5. customdried

Sources & evidence

ORD record
ord-ee0029535a2946499ced2a21f658aa00
Source dataset
uspto-grants-1992_10
Patent number
US05153195

Reaction notes

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