Hydrochloric Acid → HCID 19874117, compound

HRID 465350Notes

Reaction equation

HRID 465350 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:9]2[S:10][C:11]3[NH:12][CH2:13][CH2:14][CH2:15][C:16]=3[N:17]=2)[CH:5]=[CH:6][C:7]=1[CH3:8].[ClH:18]>>[ClH:18].[ClH:18].[NH2:1][C:2]1[CH:3]=[C:4]([C:9]2[S:10][C:11]3[NH:12][CH2:13][CH2:14][CH2:15][C:16]=3[N:17]=2)[CH:5]=[CH:6][C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 10243615HCID 10243615, compound

Product 1

HCID 19874117HCID 19874117, compoundYield 48.1%

Procedure

2-(3-Amino-4-methylphenyl)-4,5,6,7-tetrahydrothiazolo[5,4-b]pyridine was neutralized with hydrochloric acid and recrystallized from ethanol to obtain the titled compound (yield: 48.1%).

Workup

  1. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-5c28a3dc317744a484b11cff6ac8b035
Source dataset
uspto-grants-1992_10
Patent number
US05153201

Reaction notes

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