HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Peroxide → 4-(1,1-Difluoroethyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-(1,1-Difluoroethyl)benzonitrile | HCID 67181521 | — |
| Product | 4-(1,1-Difluoroethyl)benzamide | HCID 67493459 | — |
Reaction Steps
5 gm of p-CH3CF2C6H4CN, 200 ml of an aqueous solution of H2O2 at 3% and 10 ml of an aqueous solution of NaOH at 25% were reacted at 60° C. during 4 hours. A white precipitate was progressively formed. The reaction medium was then cooled, filtered, washed with water and dried under vacuum. 5.5 gm of ##STR45## were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04173706 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-714ecd5576f44734ae815878060a6599 |
| Source note | uspto-grants-1979_11 |