HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67915647, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 7-(t-Butoxycarbonyl-3-pyrrolidinyloxy)-1-cyclopropyl-5-amino-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid | HCID 15021549 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 67915647 | HCID 67915647 | — |
Reaction Steps
7-(t-Butoxycarbonyl-3-pyrrolidinyloxy)-1-cyclopropyl-5-amino-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid (105 mg), 0 5 ml of concentrated hydrochloric acid and 2 xl of acetic acid were used. The compound was treated in a similar manner to Example 1-(2) and recrystallized from ethanol, whereby 82 mg of the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05153203 |
| Source dataset | uspto-grants-1992_10 |
| ORD ID | ord-3900ce22f2204b039c24888fd7b3b878 |
| Source note | uspto-grants-1992_10 |