HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethanol → 5-(4-Acetonylbenzyl)thiazolidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethanol | HCID 8019 | — |
| Reactant | 2-Imino-5-[[4-(2-oxopropyl)phenyl]methyl]-1,3-thiazolidin-4-one | HCID 140362659 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Water | HCID 962 | — |
| Product | 5-(4-Acetonylbenzyl)thiazolidine-2,4-dione | HCID 19874526 | — |
Reaction Steps
5-(4-Acetonylbenzyl)-2-iminothiazolidine-4-one (1g) was heated under reflux in a mixture of 2-methoxyethanol 20 ml and 2N HCl (5 ml) for 8 h. The cooled mixture was diluted with water and the resulting precipitate filtered and dried under vacuum to give 5-(4-acetonylbenzyl)thiazolidine-2,4-dione as a white solid, mp 133°-135° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05153210 |
| Source dataset | uspto-grants-1992_10 |
| ORD ID | ord-ff98c89be27145a799b1af513515538d |
| Source note | uspto-grants-1992_10 |