4-Toluenesulfonyl chloride → HCID 53728733, compound

HRID 465649Notes

Reaction equation

HRID 465649 reaction equation
[NH2:1][C@@H:2]([CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:3]([NH:5][C:6]1[C:11]([F:12])=[CH:10][C:9]([F:13])=[CH:8][C:7]=1[F:14])=[O:4].[S:22](Cl)([C:25]1[CH:31]=[CH:30][C:28]([CH3:29])=[CH:27][CH:26]=1)(=[O:24])=[O:23]>>[CH3:29][C:28]1[CH:30]=[CH:31][C:25]([S:22]([NH:1][C@@H:2]([CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:3]([NH:5][C:6]2[C:7]([F:14])=[CH:8][C:9]([F:13])=[CH:10][C:11]=2[F:12])=[O:4])(=[O:24])=[O:23])=[CH:26][CH:27]=1

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 53938717HCID 53938717, compound

Product 1

HCID 53728733HCID 53728733, compound

Procedure

Following the procedure of Example 52 only using the product of Example 50 and tosyl chloride, the title compound was obtained, mp 180°-181° C.

Sources & evidence

ORD record
ord-54c4e308b74346caa69174c8fc245d92
Source dataset
uspto-grants-1992_10
Patent number
US05153226

Reaction notes

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