Water → HCID 67703958, compound

Participants

Reaction Conditions

Reaction Steps

2-Amino-6-chloropurine (Sigma, lot #69F4064, 6.0 g, 35.4 mmol) was suspended in 75mL acetonitrile. N-Methylpropylamine (Aldrich, lot #00923AW. 10.0 g, 136.7 mmol) was added and the reaction stirred at 75° C. for 24 hours. The solvents were evaporated to give an oil. Stirring the oil with water yielded a solid which was filtered and dried to give 5.9 g (28.6 mmol, 81%); mp=181°C.

Provenance & Evidence