Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | N-Methylethylamine | HCID 12219 | — |
| Reactant | 2-Amino-6-chloropurine | HCID 5360349 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 67703971 | HCID 67703971 | — |
Reaction Steps
2-Amino-6-chloropurine (Sigma, lot #69F4064, 6.5g, 38.3 mmol) was suspended in 75mL acetonitrile. N-Ethylmethylamine (6.8 g, 115.0 mmol) was added and the reaction stirred at 75° C. for 24 hours. The solvents were evaporated to give a solid which was slurried in H2O, filtered, and air dried to yield 4.86g (25.3 mmol, 66%); mp=206°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05153318 |
|---|
| Source dataset | uspto-grants-1992_10 |
|---|
| ORD ID | ord-a1da1529b94c44ba9e03b622efd2bd0d |
|---|
| Source note | uspto-grants-1992_10 |
|---|
