HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic Acid → 3-Hydroxyphthalic anhydride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic Acid | HCID 243 | — |
| Reactant | 1,3-Isobenzofurandione, 5-fluoro- | HCID 67572 | — |
| Reactant | Potassium Fluoride | HCID 522689 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | 3-Hydroxyphthalic anhydride | HCID 96580 | — |
| Product | 1,3-Dioxo-1,3-dihydro-2-benzofuran-4-yl benzoate | HCID 57047800 | — |
Reaction Steps
4-Fluorophthalic anhydride (0.44 g, 2.6 mmol shown as FPAN in table below), potassium fluoride (Aldrich, 0.14 g, 2.4 mmol), benzoic acid (Aldrich, 0.31 g, 2.5 mmol shown as BzOH in table below) and N-methyl pyrrolidinone (Aldrich, 3 ml) were heated in a 160° C. oil bath. The reaction was monitored by GC and showed the following results (BOPAN =benzoyloxyphthalic anhydride; ODPAN=oxydiphthalic anhydride; and HOPAN=hydroxyphthalic anhydride):
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05153335 |
| Source dataset | uspto-grants-1992_10 |
| ORD ID | ord-ea5c9c60f915492bbcb87391e03880bf |
| Source note | uspto-grants-1992_10 |