反应详情

温度

100 °C

A mixture of 5 g of cysteamine and 6 g of succinic anhydride is stirred under an inert atmosphere at a temperature of about 100° C. The transformation of the starting products is practically total one-half hour after the beginning of the reaction. The mixture is dissolved in 50 cm3 of water to which are added, with stirring, 5 g of sulfonic acid resin and 3 g of zinc powder to transform the disulfide present in the mixture. The resin is removed by filtration and the filtrate is concentrated under reduced pressure. After drying, 9 g of N-(2-mercapto ethyl) succinamic acid are obtained whose characteristics are identical to those of the acid obtained following the procedure of section (a), above.

1. waitThe transformation of the starting products is practically total one-half hour
2. customafter the beginning of the reaction
3. additionare added
4. stirringwith stirring
5. customThe resin is removed by filtration
6. concentrationthe filtrate is concentrated under reduced pressure
7. customAfter drying