HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2,2-Dimethyl-4-(methylsulfonyl)-1-nitrosopiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 1-Methanesulfonyl-3,3-dimethylpiperazine | HCID 19815142 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2,2-Dimethyl-4-(methylsulfonyl)-1-nitrosopiperazine | HCID 19815146 | — |
Reaction Steps
A mixture, cooled to 0°-5° C., of 45 g of 4-methanesulphonyl-2,2-dimethylpiperazine, 19.3 g of sodium nitrite, 250 ml of water and 100 ml of methanol is adjusted to pH 1.0 using conc. HCl and stirred at a gradually increasing temperature for 12 hours. The precipitate is filtered off with suction, washed with water and dried in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05155109 |
| Source dataset | uspto-grants-1992_10 |
| ORD ID | ord-1a5f840b5d8c4f4397db40ac7039863c |
| Source note | uspto-grants-1992_10 |