反应详情

温度

50 °C

4.1 g (0.03 mol) of 3H-oxazolo[4,5-b]pyridin-2-one are dissolved in 100 ml of alcohol at 95° C. 2.88 g (0.33 mol) of morpholine and then 3 ml of 30% aqueous formaldehyde solution are added. The mixture is stirred on a water bath at a temperature in the region of 50° C. for one hour 30 minutes, stirring being maintained. The mixture is left to stand for one hour at room temperature. The crystals are drained and recrystallized.

1. stirringstirring
2. temperaturebeing maintained
3. waitThe mixture is left
4. waitto stand for one hour at room temperature
5. customrecrystallized