反应详情

A mixture of 2-phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde (15.0 g), rhodanine (9.44 g), sodium acetate (16.6 g) and glacial acetic acid (90 ml) was refluxed for 10 hours. Water (200 ml) and ethyl acetate (90 ml) were added to the reaction mixture and the resulting precipitates were collected by filtration to give 5-(2-phenylpyrazolo[1,5-a]pyridine-3-yl)methylenerhodanine (cis and trans mixture) (19.8 g).

1. temperaturewas refluxed for 10 hours
2. customthe resulting precipitates
3. filtrationwere collected by filtration