HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 3-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-2-hydroxyiminopropionic acid | HCID 53679428 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | 2-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)acetonitrile | HCID 15158175 | 63.3% |
Reaction Steps
A solution of 3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2-hydroxyiminopropionic acid (0.20 g) in acetic anhydride (1 ml) was stirred for an hour at 80° C. After cooling to the mixture was added water (10 ml). The resulting precipitates were collected by filtration to give 2-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)acetonitrile (0.10 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05155114 |
| Source dataset | uspto-grants-1992_10 |
| ORD ID | ord-b368828b07294ecd8abef5b55c62c453 |
| Source note | uspto-grants-1992_10 |