Valeryl chloride → HCID 14049622, compound

HRID 466132Notes

Reaction equation

HRID 466132 reaction equation
C[Si](C)(C)[O:3][C:4]1[CH:9]=[C:8]([O:10][Si](C)(C)C)[CH:7]=[CH:6][N:5]=1.[C:17](Cl)(=[O:22])[CH2:18][CH2:19][CH2:20][CH3:21]>ClCCl>[C:17]([O:3][C:4]1[CH:9]=[C:8]([O:10][C:4](=[O:3])[CH2:9][CH2:8][CH2:7][CH3:6])[CH:7]=[CH:6][N:5]=1)(=[O:22])[CH2:18][CH2:19][CH2:20][CH3:21]

Participants

4

Reactant 2

HCID 61186Valeryl chlorideHCID 21819823HCID 21819823, compound

Product 1

HCID 14049622HCID 14049622, compoundYield 18%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The general procedure of Example 27 was repeated using 1.00 g of 2,4-bis(trimethylsilyloxy)-pyridine, 50 ml of dichloromethane, 1.02 ml of pentanoyl chloride and 0.10 ml of stannic chloride, thereby producing 200 mg of the title compound in a yield of 18%.

Sources & evidence

ORD record
ord-34d1c4e3c68848ce97414a6baac95f68
Source dataset
uspto-grants-1992_10
Patent number
US05155113

Reaction notes

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