Methyl Isocyanate → HCID 54738692, compound

HRID 466138Notes

Reaction equation

HRID 466138 reaction equation
[CH3:1][N:2]=[C:3]=[O:4].[OH:5][C:6]1[CH:11]=[CH:10][NH:9][C:8](=[O:12])[CH:7]=1>N1C=CC=CC=1>[CH3:1][NH:2][C:3]([N:9]1[CH:10]=[CH:11][C:6]([OH:5])=[CH:7][C:8]1=[O:12])=[O:4]

Participants

4

Reactant 2

HCID 12228Methyl IsocyanateHCID 546960044-Hydroxy-2(1H)-pyridinone

Product 1

HCID 54738692HCID 54738692, compoundYield 30%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

A 0.64 ml quantity of methyl isocyanate was added to a suspension of 1.00 g of 4-hydroxy-2-pyridone in 20 ml of pyridine and the mixture was stirred at room temperature for one hour. Thereafter the general procedure of Example 36 was followed to produce the title compound in a yield of 30%.

Sources & evidence

ORD record
ord-45181d468ecc408183419b6cdb8902f6
Source dataset
uspto-grants-1992_10
Patent number
US05155113

Reaction notes

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