1-Naphthalenecarbonyl chloride → HCID 14049610, compound

HRID 466157Notes

Reaction equation

HRID 466157 reaction equation
[Cl:1][C:2]1[C:3]([OH:9])=[CH:4][C:5](=[O:8])[NH:6][CH:7]=1.[C:10]1([C:20](Cl)=[O:21])[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:13]=[CH:12][CH:11]=1>N1C=CC=CC=1>[Cl:1][C:2]1[C:3]([O:9][C:20]([C:10]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH:13]=[CH:12][CH:11]=2)=[O:21])=[CH:4][C:5]([O:8][C:20]([C:10]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH:13]=[CH:12][CH:11]=2)=[O:21])=[N:6][CH:7]=1

Participants

4

Reactant 2

HCID 701461-Naphthalenecarbonyl chlorideHCID 54679224Gimeracil

Product 1

HCID 14049610HCID 14049610, compoundYield 81.9%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The general procedure of Example 45 was followed using 2.00 g of 5-chloro-4-hydroxy-2-pyridone, 3.93 g of α-naphthoyl chloride and 100 ml of pyridine, thereby producing 3.83 g of the title compound in a yield of 61%.

Sources & evidence

ORD record
ord-dddd551d659c4d85a9973704360f446b
Source dataset
uspto-grants-1992_10
Patent number
US05155113

Reaction notes

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