Potassium Carbonate → HCID 14183037, compound

HRID 466211Notes

Reaction equation

HRID 466211 reaction equation
C([O:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[C:8]([O:15][CH2:16][CH3:17])=[CH:7][C:6]=1[O:18][CH2:19][CH3:20])(=O)C.C(=O)([O-])[O-].[K+].[K+]>CO.O>[OH:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[C:8]([O:15][CH2:16][CH3:17])=[CH:7][C:6]=1[O:18][CH2:19][CH3:20]

Participants

5

Reactant 2

HCID 11430Potassium CarbonateHCID 14183036HCID 14183036, compound

Product 1

HCID 14183037HCID 14183037, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

A solution of 1-acetyloxy-2,4-diethoxynaphthalene (2.74 g) in 100 ml of methanol and 10 ml of water was stirred with 2.5 g of potassium carbonate for 6 hours. The solvent was then removed under reduced pressure, and the residue partitioned between ethyl acetate and water. The ethyl acetate layer was dried over anhydrous sodium sulfate and evaporated to a solid, which was recrystallized from ethyl acetate/hexane to give 1-hydroxy-2,4-diethoxynaphthalene, m.p. 83°-84° C.

Workup

  1. customThe solvent was then removed under reduced pressure
  2. customthe residue partitioned between ethyl acetate and water
  3. dry with materialThe ethyl acetate layer was dried over anhydrous sodium sulfate
  4. customevaporated to a solid, which
  5. customwas recrystallized from ethyl acetate/hexane

Sources & evidence

ORD record
ord-f520bf77ec9e48d482596c5ddc5a590e
Source dataset
uspto-grants-1992_10
Patent number
US05155132

Reaction notes

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