反应详情

3-[4-[(Methanesulfonyl)amino]phenyl]propionic acid benzyl ester from Preparation 26 (5.0 g (0.015 mol) and 0.75 g of 5% Pd/C catalyst in 150 ml of ethanol is hydrogenated on the Parr hydrogenator for 20 min. The mixture is filtered through a pad of Celite. The filtrate is concentrated to give a solid. It is recrystallized from ethanol to give 3-[4-[(methanesulfonyl)amino]phenyl]propionic acid; m.p. 152.5°-154° C.

1. filtrationThe mixture is filtered through a pad of Celite
2. concentrationThe filtrate is concentrated
3. customto give a solid
4. customIt is recrystallized from ethanol