HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-[4-[(Methanesulfonyl)amino]phenyl]propionic acid benzyl ester → 3-[4-[(Methanesulfonyl)amino]phenyl]propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-[4-[(Methanesulfonyl)amino]phenyl]propionic acid benzyl ester | HCID 54078088 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-[4-[(Methanesulfonyl)amino]phenyl]propionic acid | HCID 13528372 | — |
Reaction Steps
3-[4-[(Methanesulfonyl)amino]phenyl]propionic acid benzyl ester from Preparation 26 (5.0 g (0.015 mol) and 0.75 g of 5% Pd/C catalyst in 150 ml of ethanol is hydrogenated on the Parr hydrogenator for 20 min. The mixture is filtered through a pad of Celite. The filtrate is concentrated to give a solid. It is recrystallized from ethanol to give 3-[4-[(methanesulfonyl)amino]phenyl]propionic acid; m.p. 152.5°-154° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05155268 |
| Source dataset | uspto-grants-1992_10 |
| ORD ID | ord-cc19dc13e2c54b3ca549ffd11066b64d |
| Source note | uspto-grants-1992_10 |