HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 2,6-Difluoro-4-methoxybenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 2,6-Difluoro-4-methoxybenzoyl chloride | HCID 2778768 | — |
| Solvent | Diglyme | HCID 8150 | — |
| Product | 2,6-Difluoro-4-methoxybenzamide | HCID 2778770 | — |
Reaction Steps
The crude acid chloride (25) was dissolved in dry diglyme (60 ml) and added dropwise at room temperature with gentle stirring to 35% ammonia (750 ml). The resulting colourless precipitate was filtered off and dried (CaCl2) in vacuo to give a colourless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05156763 |
| Source dataset | uspto-grants-1992_10 |
| ORD ID | ord-44569574662a42a0b3a3d9eed2e3c01e |
| Source note | uspto-grants-1992_10 |