HCID 178439966, compound → HCID 178439984, compound

HRID 466698Notes

Reaction equation

HRID 466698 reaction equation
Cl[C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[N:4]=[C:5]([CH2:29][CH2:30][CH3:31])[N:6]2[CH2:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[C:24]2[NH:28][N:27]=[N:26][N:25]=2)=[CH:14][CH:13]=1>C(O)C.[Pd]>[CH2:29]([C:5]1[N:6]([CH2:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=3[C:24]3[NH:28][N:27]=[N:26][N:25]=3)=[CH:14][CH:13]=2)[C:7]2[C:3]([N:4]=1)=[CH:2][N:10]=[CH:9][N:8]=2)[CH2:30][CH3:31]

Participants

4

Reactant 1

HCID 178439966HCID 178439966, compound

Product 1

HCID 178439984HCID 178439984, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

6-Chloro-8-propyl-9-(2'-(tetrazol-5-yl)biphen-4-yl)methylpurine (0.030 g) was dissolved in ethanol (2 ml) and was stirred under an atmosphere of hydrogen in presence of Pd-C(10%) (0.01 g) for 24 hours. The catalyst was filtered off and the filtrate was evaporated to dryness giving the pure desired product as a glass like solid (0.020 g).

Workup

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-65aa6e1dd5584a6d9c0cb79e0129ff5a
Source dataset
uspto-grants-1992_10
Patent number
US05157026

Reaction notes

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